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Study identifier: NCT04254263 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Adjuvant Study of Pyrotinib in HER-2 Positive Breast Cancer

Condition: Locally Advanced Breast Cancer  ·  Sponsor: RenJi Hospital

PhasePhase 3
Planned participants316
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is a prospective, randomised, multicenter, no placebo-controlled, open label study for evaluating the efficacy and safety of pyrotinib in women with residual invasive HER2-positive breast cancer after neoadjuvant chemotherapy plus anti-HER2 target therapy. The main purpose is to investigate whether pyrotinib can further reduce the risk of recurrence from previously diagnosed HER-2 positive breast cancer based on the 1-year trastuzumab standard adjuvant treatment with or without pertuzumab.

This description comes directly from the study's public registry record.

Talk to the study team

Wenjin Yin  ·  86(21)68385569  ·  followroad@163.com

Qi Lu  ·  86(21)68383364  ·  rjllb3364@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04254263