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Study identifier: NCT04250259 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

SAMe Trial for Patients With Alcoholic Cirrhosis

Condition: Alcoholic Cirrhosis  ·  Sponsor: Indiana University

PhasePhase 2
Planned participants196
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersYes

About this study

The proposed of this randomized, double blinded, placebo-controlled study is to assess the effect of SAMe compared to placebo in patients with alcoholic cirrhosis Child Class A and B. The primary objective of the study is to test relationship between SAMe (S-adenosylmethionine) supplement on liver function. The hypothesis is that SAMe supplement will improve liver function in patients with alcoholic liver disease. The improvement in liver function will lead to the reduction in all-cause mortality in patients with alcoholic cirrhosis in those who receive SAMe supplement when compared to those receiving placebo.

This description comes directly from the study's public registry record.

Talk to the study team

Maggie Hesler, B.S  ·  (317) 988-4545  ·  mshesler@iu.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Cedars-Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Indiana University HospitalIndianapolis, Indiana, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04250259