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Study identifier: NCT04245397 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

Condition: Myelodysplastic Syndromes  ·  Sponsor: Syntrix Biosystems, Inc.

PhasePhase 1
Planned participants151
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will determine the safety profile, maximum tolerated dose (MTD), dose-limiting toxicities (DLT), and recommended Phase 2 dose (RP2D) of SX-682 in the treatment of patients with Myelodysplastic Syndromes (MDS).

This description comes directly from the study's public registry record.

Talk to the study team

Aaron D Schuler, PhD  ·  253-833-8009  ·  aschuler@syntrixbio.com

Always discuss trial participation with your own doctor first.

Locations (7)

Mayo ClinicJacksonville, Florida, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
AdventHealth Medical Group & Bone Marrow Transplant at OrlandoOrlando, Florida, United StatesRecruiting
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsBaltimore, Maryland, United StatesRecruiting
Montefiore Medical CenterThe Bronx, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04245397