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Study identifier: NCT04239157 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

Condition: Chronic Myelomonocytic Leukemia · Myelodysplastic Syndrome · Recurrent Chronic Myelomonocytic Leukemia  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2
Planned participants76
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies how well canakinumab works for the treatment of low- or intermediate-risk myelodysplastic syndrome or chronic myelomonocytic leukemia. Canakinumab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread.

This description comes directly from the study's public registry record.

Talk to the study team

Guillermo Garcia-Manero  ·  713-794-3604  ·  ggarciam@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04239157