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Study identifier: NCT04230356 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Trial of Scheduled Versus Treatment Administration of Donor-Derived Viral Specific T-cells for Viral Infections After Stem Cell Transplant

Condition: Allogeneic Stell Cell Transplant · Viral Infection  ·  Sponsor: Children's Hospital Medical Center, Cincinnati

PhasePhase 2
Planned participants180
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The purpose of this research study is to learn more about the use of viral specific T-lymphocytes (VSTs) to prevent or treat viral infections that may happen after allogeneic stem cell transplant. Allogeneic means the stem cells come from another person. VSTs are cells specially designed to fight viral infections that may happen after a stem cell transplant (SCT). Stem cell transplant reduces the body's ability to fight infections. Viral infections are a common problem after transplant and can cause significant complications. Moreover, treatment of viral infections is expensive and time consuming, with families often administering prolonged treatments with intravenous anti-viral medications, or patients requiring prolonged admissions to the hospital. The medicines can also have side effects like damage to the kidneys or reduction in the blood counts, so in this study the investigators are trying to find a better way to treat these infections.

This description comes directly from the study's public registry record.

Talk to the study team

Celeste Dourson, MS  ·  513-636-7679  ·  Celeste.Dourson@cchmc.org

Jamie Wilhelm, BS  ·  513-803-1102  ·  Jamie.Wilhelm@cchmc.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04230356