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Study identifier: NCT04221035 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)

Condition: High-Risk Neuroblastoma · Patient With Insufficient Response Chemoimmunotherapy  ·  Sponsor: Gustave Roussy, Cancer Campus, Grand Paris

PhasePhase 3
Planned participants800
Who can joinAll sexes, N/A to 21 Years
Healthy volunteersNo

About this study

This is an international multicenter, open-label, randomized phase III trial including three sequential randomizations to assess efficacy of induction and consolidation chemotherapies and radiotherapy for patients with high-risk neuroblastoma.

This description comes directly from the study's public registry record.

Talk to the study team

Claudia Pasqualini, MD PhD  ·  +33 (0)1 42 11 42 11  ·  claudia.pasqualini@gustaveroussy.fr

Habiba Attalah, PhD  ·  +33 (0)1 42 11 64 46  ·  habiba.attalah@gustaveroussy.fr

Always discuss trial participation with your own doctor first.

Locations (142)

Sydney children HospitalSydney, Randwick, AustraliaRecruiting
Children's Cancer Centre, Monash Children's HospitalClayton, AustraliaRecruiting
Oncology/Haematology Department, Perth Children's HospitalNedlands, AustraliaSuspended
Children's Cancer & Haematology Services, John Hunter Children's HospitalNew Lambton Heights, AustraliaRecruiting
Australian and New Zealand Children's Hematology/oncology GroupSydney, AustraliaActive Not Recruiting
sydney children HospitalSydney, AustraliaRecruiting
Cancer Centre for Children, The Children's HospitalWestmead, AustraliaSuspended
Medical University GrazGraz, AustriaRecruiting
Landeskrankenhaus-Universitätsklinikum InnsbruckInnsbruck, AustriaRecruiting
Kepler Universitatsklinikum LinzLinz, AustriaRecruiting
Universitastsklinikum SalzburgSalzburg, AustriaRecruiting
St Anna'S Children HospitalVienna, AustriaRecruiting

+ 130 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04221035