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Study identifier: NCT04220047 Synced from ClinicalTrials.gov · July 28, 2026
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Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass

Condition: Coronary Artery Disease · Stroke · Atrial Fibrillation  ·  Sponsor: China National Center for Cardiovascular Diseases

PhaseNA
Planned participants400
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Surgical occlusion of the left atrial appendage (LAAO) is sometimes performed during the cardiac surgery to reduce long-term risk of stroke.A previous study found that LAAO may be associated with increased risk of postoperative atrial fibrillation.New-onset atrial fibrillation (NOAF) after coronary artery bypass graft is related to an increased short-term and long term risk of stroke and mortality.Marshall ligament amputation may reduce the occurence of atrial fibrillation. However, little is known whether this approach is justified during the coronary artery bypass graft.Therefore, this study aimed to investigate whether LAAO and Marshall ligament amputation during off-pump coronary artery bypass was associated with reduced risks of postoperative new-onset atrial fibrillation and stroke.

This description comes directly from the study's public registry record.

Talk to the study team

Hengchao Wu, doctor  ·  010-88322355  ·  whcwuhengchao@163.com

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Locations (1)

Fuwai HospitalBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04220047