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Study identifier: NCT04218617 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Condition: Spine Metastases · Spine Stereotactic Radiosurgery (sSRS)  ·  Sponsor: Case Comprehensive Cancer Center

PhasePhase 2
Planned participants130
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away from normal tissue. One of the side effects of spine SRS is the development of vertebral compression fractures, many of which are not painful. The goal of this study is to compare the effects, good and/or bad, of spine SRS given in 1 or 2 treatments. Our main goal is to find out which approach will reduce the chances of developing vertebral compression fractures.

This description comes directly from the study's public registry record.

Talk to the study team

Samuel T Chao, MD  ·  1-866-223-8100  ·  TaussigResearch@ccf.org

Ehsan Balagamwala, MD  ·  1-866-223-8100  ·  balagae@ccf.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer CenterCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04218617