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Study identifier: NCT04203901 Synced from ClinicalTrials.gov · July 27, 2026
● Terminated

Dendritic Cell Immunotherapy Plus Standard Treatment of Advanced Renal Cell Carcinoma

Condition: Advanced Renal Cell Carcinoma  ·  Sponsor: CoImmune

PhasePhase 2
Planned participants16
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

CMN-001 is an autologous, tumor antigen-loaded dendritic cell immunotherapy. The active components of CMN-001 are autologous, matured dendritic cells, which have been co-electroporated with both in vitro transcribed (IVT) RNA from an autologous tumor specimen and CD40L RNA. CMN-001 is indicated for treatment of intermediate/poor risk patients with advanced renal cell carcinoma (RCC) in combination with nivolumab plus ipilimumab as first line therapy and in combination with lenvatinib plus everolimus as 2nd line therapy post 1st line failure.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (9)

Moffitt Cancer CenterTampa, Florida, United States
Emory UniversityAtlanta, Georgia, United States
Mayo ClinicRochester, Minnesota, United States
SUNY Upstate Medical UniversitySyracuse, New York, United States
Westchester Medical CenterValhalla, New York, United States
UPMC Hillman Cancer CenterPittsburgh, Pennsylvania, United States
Houston MethodistHouston, Texas, United States
MD Anderson Cancer CenterHouston, Texas, United States
West Virginia University Cancer InstituteMorgantown, West Virginia, United States

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Source record: clinicaltrials.gov/study/NCT04203901