Condition: Healthy Volunteer · Without Hearing Disorders · Sponsor: University Hospital, Clermont-Ferrand
Acoustic overexposure can induced temporary or hearing loss. Usually hearing loss is associated with cochlear cell damages. Recently, a new pathological entity was described and called "hidden hearing loss". In animal model, the histopathology revealed a selective reduction in the number of auditory fibers, resulting in a decrease in the amplitude of wave I of the auditory brainstem response. Electrocochleography (Ecog) is a method for recording the electrical potentials of the cochlea (e.g. wave I). In clinical routine, Ecog is performed invasively with sedation or local anesthesia. Actually, a non invasive approach could be perform but it seems necessary to optimize this method and to define reference values in healthy volunteers.
This description comes directly from the study's public registry record.
Lise Laclautre · 334.73.754.963 · promo_interne_drci@chu-clermontferrand.fr
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| Chu Clermont Ferrand | Clermont-Ferrand, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04198909