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Study identifier: NCT04183608 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Trial COmparing staNdard of Care Versus Treat to Target With telemonitoRing and Patient Education in Patients With Ulcerative cOlitis Initiating Adalimumab

Condition: Ulcerative Colitis  ·  Sponsor: Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives

PhasePhase 4
Planned participants238
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

PHASE: IV DESCRIPTIVE: Randomized, interventional, open label multicenter trial POPULATION: Moderate to severe ulcerative colitis STUDY TREATMENTS: Patients will all receive Adalimumab 160/80/40mg EOW until V1 (W14) followed by 40mg EOW until V2 (W26) and could be optimized up to 80mg EOW (or 40 EW according to patient and/or investigator preference) for two months and then could be optimized up to 80mg EOW (or 40 EW according to patient and/or investigator preference) and azathioprine (2.0/2.5 mg/kg/ day) or methotrexate (25 mg EW) until V3 (W 38). OBJECTIVES: To assess the impact of a treat to target treatment follow up by e-Monitoring and fecal calprotectin dosing at home associated to an appropriate patient education versus standard treatment follow up at W48 in patients requiring a treatment with adalimumab (Humira®).

This description comes directly from the study's public registry record.

Talk to the study team

Xavier Hebuterne, MD PhD  ·  04 92 03 65 75  ·  hebuterne.x@chu-nice.fr

Always discuss trial participation with your own doctor first.

Locations (24)

Centre hospitalier de CholetCholet, Maine Et Loire, FranceActive Not Recruiting
CHU Amiens- Picardie (site Sud)Amiens, FranceRecruiting
CHRU de Besançon - Hôpital Jean MinjozBesançon, FranceActive Not Recruiting
CHU Caen Hôpital Côte de NacreCaen, FranceWithdrawn
CHU EstaingClermont-Ferrand, FranceRecruiting
APHP - Hôpital BeaujonClichy, FranceRecruiting
CH Colmar - Hôpital PasteurColmar, FranceActive Not Recruiting
Centre hospitalier de DouaiDouai, FranceTerminated
CHRU Lille Hôpital Claude HuriezLille, FranceRecruiting
APHM - Hôpital NordMarseille, FranceRecruiting
GHI Le Raincy-MontfermeilMontfermeil, FranceRecruiting
CHU Montpellier - Hôpital Saint EloiMontpellier, FranceRecruiting

+ 12 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04183608