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Study identifier: NCT04180215 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

A Phase 1/2 Study in Patients With HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Other Cancers

Condition: HPV-Related Squamous Cell Carcinoma  ·  Sponsor: Hookipa Biotech GmbH

PhasePhase 1/Phase 2
Planned participants198
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a First in Human (FIH) Phase I/II, multinational, multicenter, open-label study of HB-201 single vector therapy and HB-201 \& HB-202 two-vector therapy in patients with HPV 16+ confirmed cancers comprising two parts: Phase I Dose Escalation and Phase II Dose Expansion.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (34)

O'Neal Comprehensive Cancer Center at UABBirmingham, Alabama, United States
Banner MD Anderson Cancer CenterGilbert, Arizona, United States
University of Arkansas for Medical Sciences, Cancer Institute, Clinical Trials OfficeFayetteville, Arkansas, United States
USC/Norris Comprehensive Cancer CenterLos Angeles, California, United States
UCLA (University of California, Los Angeles)Los Angeles, California, United States
Sylvester Comprehensive Cancer CenterMiami, Florida, United States
University of Chicago Medical CenterChicago, Illinois, United States
Loyola University Medical SchoolMaywood, Illinois, United States
University of Iowa Hospitals & ClinicsIowa City, Iowa, United States
University of Kansas Medical CenterFairway, Kansas, United States
Henry Ford HospitalDetroit, Michigan, United States
Washington University School of MedicineSt Louis, Missouri, United States

+ 22 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04180215