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Study identifier: NCT04173650 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

MSC EVs in Dystrophic Epidermolysis Bullosa

Condition: Dystrophic Epidermolysis Bullosa  ·  Sponsor: Aegle Therapeutics

PhasePhase 1/Phase 2
Planned participants8
Who can joinAll sexes, 6 Months to no upper limit
Healthy volunteersNo

About this study

INVESTIGATIONAL PRODUCT: AGLE-102 is an allogeneic extracellular vesicle (EV) product derived from normal donor mesenchymal stem cells (MSCs). INDICATION AND RATIONALE: The aim of the study is to assess the safety and efficacy of AGLE-102 in the treatment of lesions in subjects with Epidermolysis Bullosa (EB). STUDY DESIGN: This is a phase 1/2A, randomized, multi-center, study to assess the effectiveness and safety of AGLE-102 on lesions in subjects with EB.

This description comes directly from the study's public registry record.

Talk to the study team

Mei Chen, Ph.D.  ·  323-865-0621  ·  chenm@usc.edu

Always discuss trial participation with your own doctor first.

Locations (3)

Phoenix Children's HospitalPhoenix, Arizona, United StatesRecruiting
USC /Norris Comprehensive Cancer Center University of Southern CaliforniaLos Angeles, California, United StatesRecruiting
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04173650