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Study identifier: NCT04167969 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer

Condition: Prostate Cancer  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 1
Planned participants16
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to see whether using the copper-64 (64Cu) or zirconium-89 (89Zr) radiolabeled PSMA-targeting C' dot tracer, termed 64Cu-NOTA-PSMAi-PEG-Cy5.5-C' dots or 89Zr-DFO-PSMAi-PEG-Cy5.5-C' dots, is a safe way to identify tumor cells before and during surgery for prostate cancer. The researchers want to determine whether pre-operative PET/MRI scans and intra-operative optical imaging performed in prostate cancer patients after the injection of one of these investigational tracers more accurately localizes cancerous deposits within the surgical bed as compared with conventional imaging scans alone. The researchers will study how the tracer travels through your body and where it is distributed. This study is the first time that the tracer will be used in patients undergoing surgery for prostate cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Hong Truong, MD, MS  ·  646-422-4360  ·  truongh1@mskcc.org

Heiko Schoder, MD  ·  212-639-8001

Always discuss trial participation with your own doctor first.

Locations (2)

Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Weill Cornell MedicineNew York, New York, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04167969