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Study identifier: NCT04160507 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Duke APOL1 Research Biorepository

Condition: End Stage Kidney Disease  ·  Sponsor: Duke University

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The Duke ApoL1 Nephropathy Biorepository aims to address needs within non-diabetic kidney failure research by utilizing existing and, when necessary, developing new infrastructure to support the consent of patients and the collection of dedicated samples for ApoL1 Nephropathy biorepository. The mutations in ApoL1 gene that are strongly associated with kidney disease are only present in individuals of recent African ancestry (i.e., black people). Caucasians do not have these ApoL1 mutations nor the associated kidney disease. Therefore, majority of subjects recruited for this study will be self-identified African Americans, Afro-Caribbean and other black individual. Study subjects will include individuals with end stage kidney disease and those without any clinical evidence of kidney disease. Additionally, healthy black adults with no known history of kidney disease will be recruited as controls in this study because they are the only group that can fill this role.

This description comes directly from the study's public registry record.

Talk to the study team

Opeyemi Olabisi, MD/PHD  ·  919-660-6987  ·  opeyemi.olabisi@duke.edu

Maurice W Smith, MA  ·  9196131386  ·  maurice.w.smith@duke.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Duke University Medical CenterDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04160507