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Study identifier: NCT04150497 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01)

Condition: B-cell Acute Lymphoblastic Leukemia  ·  Sponsor: Cellectis S.A.

PhasePhase 1/Phase 2
Planned participants52
Who can joinAll sexes, 15 Years to 50 Years
Healthy volunteersNo

About this study

This is a first-in-human, open-label, dose escalation and expansion study of UCART22 administered intravenously to patients with relapsed or refractory B-cell acute Lymphoblastic Leukemia (B-ALL). The purpose of this study is to evaluate the safety and clinical activity of UCART22 and determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D)

This description comes directly from the study's public registry record.

Talk to the study team

Cellectis Central Contact  ·  +1 (347) 752-4044  ·  clinicaltrials@cellectis.com

Always discuss trial participation with your own doctor first.

Locations (19)

University of California, Los Angeles (UCLA) - Medical CenterLos Angeles, California, United StatesRecruiting
University of Colorado - Aurora Cancer CenterAurora, Colorado, United StatesRecruiting
Sarah Cannon - Colorado Blood Cancer InstituteDenver, Colorado, United StatesRecruiting
University of ChicagoChicago, Illinois, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Roswell Park Comprehensive Cancer CenterBuffalo, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (MSKCC) David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Weill Medical College of Cornell UniversityNew York, New York, United StatesWithdrawn
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting
Sarah Cannon - HCA Research InstituteNashville, Tennessee, United StatesRecruiting
Sarah Cannon - St. David's South Austin Medical CenterAustin, Texas, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting

+ 7 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04150497