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Study identifier: NCT04147286 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Atorvastatin to Reduce Inflammation After Tuberculosis Treatment Completion

Condition: Tuberculosis, Pulmonary  ·  Sponsor: University of Cape Town

PhasePhase 2/Phase 3
Planned participants220
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This is a proof-of-concept phase IIB, double-blind, randomized, placebo-controlled trial to evaluate the safety and efficacy of 40 mg atorvastatin to reduce persistent lung inflammation after successful TB treatment completion in HIV-infected and HIV-uninfected adults measured by PET/CT.

This description comes directly from the study's public registry record.

Talk to the study team

Friedrich Thienemann, MD  ·  +27 21 406 6358  ·  friedrich.thienemann@uct.ac.za

Sandra Mukasa, MD  ·  +27 21 406 6358  ·  sandra.mukasa@uct.ac.za

Always discuss trial participation with your own doctor first.

Locations (1)

General Medicine & Global Health, Cape Heart Institute, Faculty of Health Sciences, University of Cape TownObservatory, WC, South AfricaRecruiting

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Source record: clinicaltrials.gov/study/NCT04147286