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Study identifier: NCT04144972 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Condition: Spinal Cord Injuries · Nerve Injury · Pain, Postoperative  ·  Sponsor: University of California, San Francisco

PhaseNA
Planned participants12
Who can joinAll sexes, 22 Years to 80 Years
Healthy volunteersNo

About this study

Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and provide continuous 24/7 brain stimulation which may lose effect over time. By developing new technology that targets multiple, complimentary brain regions in an adaptive fashion, the investigators will test a new therapy for chronic pain that has potential for better, more enduring analgesia.

This description comes directly from the study's public registry record.

Talk to the study team

Catherine Borror  ·  ‪(415) 353-3494  ·  chronicpain@ucsf.edu

Prasad Shirvalkar, M.D., Ph.D  ·  ‪(415) 691-7587‬  ·  Prasad.Shirvalkar@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California, San FranciscoSan Francisco, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04144972