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Study identifier: NCT04134780 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Ultrasound Imaging and Spectroscopy as Early Indicators of Locally-Advanced Breast Cancer Response

Condition: Breast Cancer  ·  Sponsor: Sunnybrook Health Sciences Centre

PhaseN/A
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This work explores the possibility of using ultrasound imaging and spectroscopy as a way of monitoring cell death, hence, tumour response to treatment. The hypothesis here is that it can be used as a way of monitoring early response to cancer treatment and predicting which patients continue on in their therapy to have a complete pathological response as a primary endpoint and tumour size decrease as a secondary endpoint. If this work is successful it could be used in the future early on in a cancer patient's treatment to predict whether or not a course of chemotherapy or radiotherapy is going to be successful. For example, in patients in which the analysis indicates a poor response the chemotherapy regimen could be changed to a more efficacious one or for those receiving radiotherapy predicted to have a poor response a radiosensitizing agent could be used to improve outcome.

This description comes directly from the study's public registry record.

Talk to the study team

Gregory J Czarnota, PhD, MD  ·  (416) 480-6128  ·  gregory.czarnota@sunnybrook.ca

Always discuss trial participation with your own doctor first.

Locations (3)

MD AndersonHouston, Texas, United StatesCompleted
Sunnybrook Health Sciences CentreToronto, Ontario, CanadaRecruiting
Princess Margaret Cancer CentreToronto, Ontario, CanadaCompleted

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Source record: clinicaltrials.gov/study/NCT04134780