Condition: Osteosarcoma · Sponsor: University College, London
There has been little improvement in outcome for patients with osteosarcoma (OS) over the last 20 years. There have been only a few clinical trials of new treatments and no major new therapies introduced recently. This is in part because there is no good understanding of the biology of osteosarcoma, but also trials have only included subgroups of patients. The more that is understood about how and why osteosarcoma arises and grows the better clinicians will be able to decide what treatments are most likely to work best. The purpose of this project is to collect high quality clinical data about patients of all ages with osteosarcoma, such as information about the size of the disease, how it was diagnosed and where it is at diagnosis, what treatments were given and how the disease responded the treatments. Blood and tissue samples will also be collected for analysis in research laboratories. By looking at the results of the laboratory findings and the clinical data together, the questions will start to be answered about why osteosarcomas arise and grow, what makes it spread, and why some patients respond to treatment better than others. As time goes on, this information is planned to be used to develop clinical trials of new treatments. Alongside this, the aim is to find out more about how osteosarcoma and its treatments affect the lives of those living with this disease. This information will help provide the most appropriate care and support that will meet the needs of eac…
This description comes directly from the study's public registry record.
Krystyna Reczko · 020 7679 9878 · ctc.iconic@ucl.ac.uk
Rubina Begum · 020 7679 9514 · ctc.iconic@ucl.ac.uk
Always discuss trial participation with your own doctor first.
| University College Hospitals London NHS Foundation Trust | London, Greater London, United Kingdom | Recruiting |
| NHS Grampian Health Board | Aberdeen, United Kingdom | Recruiting |
| Birmingham Women's and Childrens NHS Foundation Trust | Birmingham, United Kingdom | Recruiting |
| The Royal Orthopaedic Hospital NHS Foundation Trust | Birmingham, United Kingdom | Recruiting |
| University Hospitals Birmingham NHS Foundation Trust | Birmingham, United Kingdom | Recruiting |
| Cambridge University Hospitals NHS Foundation Trust | Cambridge, United Kingdom | Recruiting |
| Cardiff and Vale University LHB | Cardiff, United Kingdom | Recruiting |
| NHS Lothian Health Board | Edinburgh, United Kingdom | Recruiting |
| NHS Greater Glasgow and Clyde Health Board | Glasgow, United Kingdom | Recruiting |
| Leeds Teaching Hospitals NHS Trust | Leeds, United Kingdom | Recruiting |
| University Hospitals of Leicester NHS Trust | Leicester, United Kingdom | Recruiting |
| Alder Hey Children's NHS Foundation Trust | Liverpool, United Kingdom | Recruiting |
+ 10 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04132895