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Study identifier: NCT04131413 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

Condition: Human Papillomavirus Type 16 · Cervical Intraepithelial Neoplasia Grade II · Cervical Intraepithelial Neoplasia, Grade III  ·  Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

PhasePhase 1
Planned participants48
Who can joinFemale, 19 Years to no upper limit
Healthy volunteersYes

About this study

The primary goal of this phase I open label study is to determine the safety and tolerability of pNGVL4aCRTE6E7L2 DNA vaccine, as administered by intramuscular (IM) injection with TriGrid™ electroporation to both HIV- or HIV+ adult female subjects (≥ 19 years), with biopsy confirmed cervical intraepithelial (CIN) II or III that is human papillomavirus (HPV) 16+.

This description comes directly from the study's public registry record.

Talk to the study team

Kimberly Levinson, MD  ·  4109558240  ·  klevins1@jhmi.edu

Ashish Solanki, RN  ·  410-614-6702  ·  asolank2@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04131413