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Study identifier: NCT04119713 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Autoimmunity After Checkpoint Blockade

Condition: Autoimmunity · Cancer · Immunotoxicity  ·  Sponsor: Abramson Cancer Center at Penn Medicine

PhaseN/A
Planned participants600
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to better understand how the treatment of cancer with immune checkpoint inhibitors (ICI) leads to the development of autoimmunity. Specifically, we wish to understand the genetics and immune system features that cause a subset of cancer patients treated with checkpoint inhibitor therapy to develop an immune-related adverse event (irAE).

This description comes directly from the study's public registry record.

Talk to the study team

Kyra J Sacksith  ·  215-898-9339  ·  kyra.sacksith@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Pennsylvania - Abramson Cancer CenterPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04119713