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Study identifier: NCT04110756 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

ChangeGradients: Promoting Adolescent Health Behavior Change

Condition: Alcohol Drinking · Self Efficacy · Adolescent Behavior  ·  Sponsor: University of California, San Francisco

PhaseNA
Planned participants200
Who can joinAll sexes, 15 Years to 17 Years
Healthy volunteersYes

About this study

As most adolescents visit a healthcare provider once a year, health behavior change interventions linked to clinic-based health information technologies hold significant promise for improving healthcare quality and subsequent behavioral health outcomes for adolescents (Baird, 2014, Harris, 2017). Recognizing the potential to leverage recent advances in machine learning and interactive narrative environments, the investigators are now well positioned to design health behavior change systems that extend the reach of clinicians to realize significant impacts on behavior change for adolescent preventive health. The proposed project centers on the design, development, and evaluation of a clinically-integrated health behavior change system for adolescents. CHANGEGRADIENTS will introduce an innovative reinforcement learning-based feedback loop in which adolescent patients interact with personalized behavior change interactive narratives that are dynamically personalized and realized in a rich narrative-centered virtual environment. CHANGEGRADIENTS will iteratively improve its behavior change models using policy gradient methods for Reinforcement Learning (RL) designed to optimize adolescents' achieved behavior change outcomes. This in turn will enable CHANGEGRADIENTS to generate more effective behavior change narratives, which will then lead to further improved behavior change outcomes. With a focus on risky behaviors and an emphasis on alcohol use, adolescents will interact with C…

This description comes directly from the study's public registry record.

Talk to the study team

Elizabeth M Ozer, PhD  ·  415-819-6337  ·  elizabeth.ozer@ucsf.edu

Alison S Giovanelli, PhD  ·  805-405-0772  ·  alison.giovanelli@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California San Francisco Adolescent and Young Adult Medicine ClinicSan Francisco, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04110756