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Study identifier: NCT04109079 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

Condition: Breast Cancer · Sentinel Lymph Node · Neoplasm, Breast  ·  Sponsor: University Hospitals of Derby and Burton NHS Foundation Trust

PhaseNA
Planned participants1900
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this study is to assess whether, omitting further axillary treatment (ALND and ART) for patients with early stage breast cancer and axillary nodal metastases on needle biopsy, who after NACT have no residual cancer in the lymph nodes on sentinel node biopsy, is non-inferior to axillary treatment in terms of disease free survival (DFS) and results in reduced risk of lymphoedema at 5 years.

This description comes directly from the study's public registry record.

Talk to the study team

Amit Goyal, MS, MD, FRCS  ·  +44 1332785538  ·  amit.goyal@nhs.net

Always discuss trial participation with your own doctor first.

Locations (98)

St Vincent's University Hospital - St Vincent's Healthcare GroupDublin, IrelandRecruiting
St Luke's Hospital - St Luke's Radiation Oncology NetworkDublin, IrelandRecruiting
Beaumont Hospital - Royal College of Surgeons in IrelandDublin, IrelandRecruiting
Galway University Hospitals - Saolta University Health Care GroupGalway, IrelandRecruiting
Airedale General Hospital - Airedale NHS Foundation TrustKeighley, BD20 6TD, United KingdomRecruiting
Cumberland Infirmary - North Cumbria Integrated Care NHS Foundation TrustCarlisle, CA2 7HY, United KingdomRecruiting
Frimley Park Hospital - Frimley Health NHS Foundation TrustCamberley, GU16 7UJ, United KingdomRecruiting
Raigmore Hospital - NHS HighlandInverness, IV2 3UJ, United KingdomRecruiting
James Paget Hospital -James Paget University Hospitals NHS Foundation TrustGreat Yarmouth, NR31 6LA, United KingdomRecruiting
Royal Berkshire Hospital - Royal Berkshire NHS Foundation TrustReading, RG1 5AN, United KingdomRecruiting
Macclesfield District General Hospital - East Cheshire NHS TrustMacclesfield, SK10 3BL., United KingdomRecruiting
Royal Shrewsbury Hospital -The Shrewsbury and Telford Hospitals NHS TrustShrewsbury, SY3 8XQ, United KingdomRecruiting

+ 86 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04109079