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Study identifier: NCT04106518 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Genetic Determinants in Alcoholic Hepatitis and Establishment of a Multicenter Prospective Cohort of Patients With Alcoholic Liver Disease

Condition: Alcoholic Liver Disease · Severe Alcoholic Hepatitis · Alcoholic Cirrhosis  ·  Sponsor: University Hospital, Lille

PhaseN/A
Planned participants447
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Alcoholic hepatitis carries a risk of high mortality at short term, especially in its severe form. Its diagnosis is confirmed by liver biopsy. The prevalence of alcoholic hepatitis, severe or not severe, is poorly known and prospective data are needed. The present observational study aims to define the prevalence of alcoholic hepatitis among patients admitted for jaundice and determine their outcome according to the severity. Survival and markers of liver dysfunction will be assessed. A biobank including genetic samples will be created to identify the disease profile in terms of inflammation and regeneration. The performance of non-invasive criteria for diagnosis will also be studied.

This description comes directly from the study's public registry record.

Talk to the study team

Alexandre Louvet, MD,PhD  ·  03 20 44 55 97  ·  alexandre.louvet@chru-lille.fr

Always discuss trial participation with your own doctor first.

Locations (9)

Chr AngersAngers, FranceRecruiting
Chru BesanconBesançon, FranceRecruiting
Hôpital Jean Verdier, AH-HPBondy, FranceRecruiting
Centre Hospitalier UniversitaireCaen, FranceRecruiting
Hopital Nord - Chu38 - La TroncheLa Tronche, FranceRecruiting
Hôpital Claude Huriez, CHULille, FranceRecruiting
Association Hopital Saint Joseph - MarseilleMarseille, FranceRecruiting
Chu MontpellierMontpellier, FranceRecruiting
Hu Est Parisien Site St Antoine Aphp - Paris 12Paris, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04106518