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Study identifier: NCT04102930 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR)

Condition: Giant Cell Arteritis · Polymyalgia Rheumatica  ·  Sponsor: University of Leeds

PhaseN/A
Planned participants4500
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

A multi-centre observational study recruiting prospective and retrospective cohorts of patients with polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). The primary aim is to find genetic determinants of GCA and PMR susceptibility, in order to yield novel insights into disease pathogenesis. A subset of the retrospective cohort is also enrolled in a post-marketing surveillance registry of patients eligible for, or receiving tocilizumab, to treat their relapsing or refractory GCA.

This description comes directly from the study's public registry record.

Talk to the study team

Louise Sorensen  ·  0113 343 7764  ·  MRCTarget@leeds.ac.uk

Always discuss trial participation with your own doctor first.

Locations (76)

Queen Elizabeth The Queen Mother HospitalCanterbury, Kent, United KingdomRecruiting
Whiston HospitalPrescot, Merseyside, United KingdomRecruiting
Nevill Hall Hospital, Aneurin Bevan University Health BoardAbergavenny, United KingdomRecruiting
Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS TrustAylesbury, United KingdomRecruiting
Betsi Cadwaladr University Health BoardBangor, United KingdomRecruiting
Barnsley Hospital, Barnsley Hospital NHS Foundation TrustBarnsley, United KingdomCompleted
Basildon University Hospital, Basildon and Thurrock University Hospitals NHS Foundation TrustBasildon, United KingdomRecruiting
Basingstoke and North Hampshire Hospital, Hampshire Hospitals NHS Foundation TrustBasingstoke, United KingdomRecruiting
Royal National Hospital for Rheumatic Diseases, Royal United Hospitals Bath NHS Foundation TrustBath, United KingdomRecruiting
Birmingham Heartlands Hospital, University Hospitals Birmingham NHS Foundation TrustBirmingham, United KingdomRecruiting
Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation TrustBirmingham, United KingdomRecruiting
Bristol Royal Infirmary, University Hospitals Bristol NHS Foundation TrustBristol, United KingdomRecruiting

+ 64 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04102930