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Study identifier: NCT04101669 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

RESET System Pivotal Trial (Rev F)

Condition: Diabetes type2 · Obesity  ·  Sponsor: Morphic Medical Inc.

PhaseNA
Planned participants264
Who can joinAll sexes, 22 Years to 65 Years
Healthy volunteersNo

About this study

A Randomized, Multi-Center, Pivotal Efficacy and Safety Study Evaluating the RESET System for Glycemic Improvement in Patients with Inadequately Controlled Type 2 Diabetes and Obesity, the STEP-1 Study. A multi-center, double-blinded, randomized, sham-controlled trial to evaluate the safety and effectiveness of the RESET System plus moderate intensity lifestyle and dietary counseling compliant with 2024 ADA Standard of Care as compared to a sham control receiving moderate intensity lifestyle and dietary counseling. Both the treatment and sham group will practice medical management compliant with STEP-1 Study Guidelines. Patients will be randomized 3 (RESET):1 (Sham).

This description comes directly from the study's public registry record.

Talk to the study team

Stephen J Linhares, BS  ·  774-454-3259  ·  slinhares@gidynamics.com

Aoife Devery, BS  ·  617-528-8880  ·  adevery@gidynamics.com

Always discuss trial participation with your own doctor first.

Locations (7)

MedStar Health Research InstituteWashington D.C., District of Columbia, United StatesRecruiting
University of Miami HospitalMiami, Florida, United StatesRecruiting
Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting
Michigan Medicine, Division of Gastroenterology and HepatologyAnn Arbor, Michigan, United StatesRecruiting
Weill Cornell MedicineNew York, New York, United StatesRecruiting
Cleveland ClinicCleveland, Ohio, United StatesRecruiting
Baylor College of MedicineHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04101669