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Study identifier: NCT04098874 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Bupropion for the Prevention of Postpartum Smoking Relapse

Condition: Postpartum Smoking Relapse  ·  Sponsor: University of Minnesota

PhasePhase 4
Planned participants200
Who can joinFemale, 18 Years to 45 Years
Healthy volunteersYes

About this study

This two-arm, double-blind, placebo-controlled randomized clinical trial will enroll pregnant women who quit smoking after learning they were pregnant and are motivated to stay abstinent postpartum. Participants will be randomized to receive extended-release bupropion (active 300mg or placebo once daily beginning 4 to 10 days postpartum to 12 weeks post-randomization). All participants will complete the same data collection procedures (e.g., biological sample collection for hormone and cotinine analysis and completion of validated questionnaires) at baseline (gestational week 36), weekly from 4 to 10 days postpartum through 12 weeks post-randomization and at weeks 12, 24, 36 and 52 post-randomization.

This description comes directly from the study's public registry record.

Talk to the study team

Katherine Harrison, MPH  ·  612-624-5377  ·  harr0644@umn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of MinnesotaMinneapolis, Minnesota, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04098874