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Study identifier: NCT04097158 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Biomarkers in Different Types of Amyotrophic Lateral Sclerosis (ALS) Patients Being Treated With Edaravone

Condition: Amyotrophic Lateral Sclerosis  ·  Sponsor: Loma Linda University

PhaseN/A
Planned participants160
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

This study is being conducted to help the investigators better understand how the new FDA approved medication Edaravone (also known as Radicava) works in subsets of patients with ALS. The investigators are also trying to understand if there are specific ALS patients, with different presentations of ALS, who might benefit most from this medication. Also, the investigators are following specific biomarkers to determine the optimal treatment duration in patients with different forms of ALS There is no study medication being offered in this trial. Edaravone is prescribed as part of regular care. In this trial we are collecting blood, urine, and spinal fluid samples in ALS patients who are taking Edaravone and ALS patients who are not taking Edaravone to measure certain markers that could indicate why the drug may be working in a specific type of ALS.

This description comes directly from the study's public registry record.

Talk to the study team

Imran Qasim  ·  (909) 558-2037  ·  sqasim@llu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Loma Linda UniversityLoma Linda, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04097158