Condition: Urinary Tract Infections · Urinary Tract Infection (UTI) · Sponsor: University Hospital, Basel, Switzerland
Urological pathogens are effected by rising antimicrobial resistance rates due to the frequent use of antimicrobials for treatment and prophylaxis. Intravesical instillation with hyaluronic acid (HA) and chondroitin sulphate (CS) obtained positive outcomes in the treatment of overactive bladder, radiation cystitis and interstitial cystitis by replenishment of the glycosaminoglycan layer of the bladder. This study is to investigate whether intravesical instillation with HA-CS in patients with recurrent urinary tract infections (rUTI) is superior to a placebo instillation in terms of reduction of rate of symptomatic urinary tract infections (UTIs) (based on clinical diagnosis) needing treatment with antimicrobials within 12 months after randomisation.
This description comes directly from the study's public registry record.
Kathrin Bausch, Dr. med · +41 61 265 72 80 · kathrin.bausch@usb.ch
Hans-Helge Seifert, Prof. Dr. MD · +41 61 265 72 80 · helge.seifert@usb.ch
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| Department of Gynecology, University Hospital Basel | Basel, Switzerland | Recruiting |
| Department of Urology, University Hospital Basel | Basel, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04095572