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Study identifier: NCT04084860 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking

Condition: Alcohol Use Disorder  ·  Sponsor: New York State Psychiatric Institute

PhasePhase 2
Planned participants120
Who can joinAll sexes, 21 Years to 70 Years
Healthy volunteersNo

About this study

The proposed project tests the efficacy of glutamate modulators in non-depressed individuals with alcohol use disorder (AUD); the primary hypothesis is that the glutamate modulator being tested reduces heavy drinking days compared to the active control. It also aims to investigate, using a 2 by 2 factorial (2x2) design, the hypothesis that the effects of the glutamate modulator are enhanced when combined with behavioral treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Kate O'Malley  ·  6467746103  ·  kate.omalley@nyspi.columbia.edu

Elias Dakwar, MD  ·  6467748728

Always discuss trial participation with your own doctor first.

Locations (1)

NYSPINew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04084860