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Study identifier: NCT04080635 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Therapeutic Drug Monitoring of Brodalumab in Psoriasis Patients (BIOLOPTIM-BRO)

Condition: Psoriasis Vulgaris  ·  Sponsor: University Hospital, Ghent

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Biologics, such as brodalumab, are currently the most effective treatment option for patients with moderate-to-severe psoriasis. But they are costly for health care systems and prescribed according to a 'one dose fits all' dosing regimen, leading to potential over- and undertreatment. Within this study we aim to investigate the predictive value of early serum trough levels of brodalumab and determine the therapeutic window of brodalumab in psoriasis patients.

This description comes directly from the study's public registry record.

Talk to the study team

Jo Lambert, Prof.  ·  09 332 22 87  ·  jo.lambert@uzgent.be

Lynda Grine, Dr.  ·  09 332 22 87  ·  lynda.grine@uzgent.be

Always discuss trial participation with your own doctor first.

Locations (7)

AZ Maria MiddelaresGhent, Oost-Vlaanderen, BelgiumNot Yet Recruiting
AZ Sint-LucasGhent, Oost-Vlaanderen, BelgiumNot Yet Recruiting
University Hospital of GhentGhent, Oost-Vlaanderen, BelgiumRecruiting
Private Practice DermatologyMaldegem, Oost-Vlaanderen, BelgiumNot Yet Recruiting
University HospitalLeuven, Vlaams-Brabant, BelgiumNot Yet Recruiting
AZ Sint-JanBruges, West-Vlaanderen, BelgiumNot Yet Recruiting
AZ Delta RembertTorhout, West-Vlaanderen, BelgiumNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04080635