Condition: Hearing Loss, Sensorineural · Bilateral Vestibular Deficiency · DFNA9 · Sponsor: Jessa Hospital
In 2014 radiologic lesions were detected at one or more semicircular canals using CT and MR imaging of temporal bone in subjects carrying the p.P51S mutation in COCH. These lesions are believed to present at more advanced stages of the hearing and vestibular deterioration. Since then, other authors have described similar lesions in advanced non-genetic hearing and vestibular impairment as well. The purpose of this study is therefore to assess the radiologic investigation using CT and MR imaging of temporal bone to all subjects presenting with bilateral vestibulopathy, using the Barany criteria, compared to the p.P51S population.
This description comes directly from the study's public registry record.
sebastien p JanssensdeVarebeke, MD · 011337420 · drsjanssens@gmail.com
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| Jessa Hospital | Hasselt, Limburg, Belgium | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04070937