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Study identifier: NCT04066465 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neurocognitive Function After Proton Therapy in Children and Adolescents

Condition: Primary Brain Tumor  ·  Sponsor: Technische Universität Dresden

PhaseN/A
Planned participants90
Who can joinAll sexes, 8 Years to 18 Years
Healthy volunteersYes

About this study

Brain tumors are the second most frequent malignant diseases in children and adolescents. In the study the short and medium term consequences of proton therapy on cognitive processes in particular on executive functions in pediatric patients shall be highlighted/analysed/evalutated. In a second step, these results are to be compared with 1. a group of children and adolescents who had only /exclusively had operative therapy and 2. with a healthy control group. Thus, the extent to which these treatment options differ in terms of their short and medium-term effect is assessed. Methods of neurocognitive/neurophysiology brain research approaches are applied that may potentially visualize even small / subtle changes in mental activities/neurocognitive function. Therefore the effects of treatment can be evaluated and the neuropsychological outcome of children and adolescents with brain tumors can be improved.

This description comes directly from the study's public registry record.

Talk to the study team

Mechthild Krause, Prof. Dr.  ·  +49 351 458 2238  ·  mechthild.krause@uniklinikum-dresden.de

Always discuss trial participation with your own doctor first.

Locations (3)

University Hospital Carl GUstav Carus Dresden, Child and adolescent psychiatry and psychotherapyDresden, Saxony, GermanyRecruiting
University Hospital Carl GUstav Carus Dresden, Department of NeuropaediatricsDresden, Saxony, GermanyRecruiting
University Hospital Carl GUstav Carus Dresden, Department of Radiation Therapy and Radiation OncologyDresden, Saxony, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT04066465