Condition: CMV · Sponsor: Instituto de Investigación Marqués de Valdecilla
Cytomegalovirus (CMV) infection is a major cause of morbidity and mortality for recipients of allogeneic hematopoietic stem cell transplantation(HSCT). Recently, strategies based on immunotherapy adoptive cells (IAC) with anti-CMV Cytolitic T Lymphocytes (CMV-CTLs) has been incorporated to prevent or treat CMV after HSCT. The aim to study donor derived CMV-CTLs after haploidentical HSCT (HAPLO) as prophylaxis for CMV infection in transplant patients. CMV-CTLs will be administer at day 21 (+-7 days) post-HAPLO. CMV DNA levels with quantitative PCR will be weekly monitored.
This description comes directly from the study's public registry record.
Miriam Sanchez-Escamilla, MD · +34646393234 · msanchez@idival.org
Lucía Lavín Alconero, Phd · eclinicos5@idival.org
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| Hospital Marques de Valdecilla | Santander, Spain | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04056533