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Study identifier: NCT04052893 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

DFS and QOL After Modified Radical Mastectomy vs. Expanded Mckissock Surgery for EIC of the Breast

Condition: Breast Neoplasms  ·  Sponsor: Shengjing Hospital

PhaseNA
Planned participants200
Who can joinFemale, 45 Years to 75 Years
Healthy volunteersNo

About this study

Extensive intraductal carcinoma of the breast refers to a type of breast cancer in which ≥ 25% of ductal carcinoma in situ is present in invasive tumors and there is a scattered distribution of ductal carcinoma in situ (DCIS) in or around the invasive carcinoma. Compared with DCIS negative for extensive intraductal component, DCIS positive for extensive intraductal component is not sensitive to radiotherapy. Mckissock surgery was applied in breast-conserving surgery for breast cancer in 2016. Jianyi Li and the team members (Shengjing Hospital of China Medical University, Shenyang, China) applied this technique in breast-conserving surgery with preservation of the nipple-areola complex. This surgical technique is suitable for low-grade malignant tumors and has better prognosis than radical mastectomy. The purpose of this study is to investigate postoperative disease-free survival and quality of life after modified radical mastectomy versus expanded Mckissock surgery for extensive intraductal carcinoma of the breast. Results from this study will indicate the efficacy of expanded Mckissock surgery in the treatment of extensive intraducatal carcinoma of the breast.

This description comes directly from the study's public registry record.

Talk to the study team

Jianyi Li  ·  +8618940257177  ·  sjbreast@yeah.net

Always discuss trial participation with your own doctor first.

Locations (3)

General Hospital of Benxi Iron & Steel Industry Group of Liaoning Health Industry GroupBenxi, Liaoning, ChinaRecruiting
Cancer Hospital of China Medical University, Liaoning Cancer Hospital and InstituteShengyang, Liaoning, ChinaRecruiting
Shengjing Hospital of China Medical UniversityShenyang, Liaoning, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04052893