Condition: Colorectal Cancer · Sponsor: Royal Marsden NHS Foundation Trust
TRACC Part B This is a multi-centre, prospective, translational research study involving the collection and analysis of tumour tissue, serial blood samples and clinical data in patients with newly diagnosed stage I, II and III CRC. TRACC Part C is a : (multi-centre, prospective, randomised study, of ctDNA guided adjuvant chemotherapy versus standard of care adjuvant chemotherapy study after curative surgery in patients with high risk stage II or stage III CRC. )It aims to demonstrate that a de-escalation strategy of ctDNA guided adjuvant chemotherapy is non- inferior to standard of care treatment as measured by 3 year disease free survival (DFS) in patients with high risk stage II or stage III colorectal cancer CRC with no evidence of minimal residual disease (MRD) (ctDNA negative)
This description comes directly from the study's public registry record.
Hsiang-Chi Chen, MSc · 02086426011 · TRACCStudy@rmh.nhs.uk
Susie Slater, Dr
Always discuss trial participation with your own doctor first.
| Milton Keynes General Hospital | Milton Keynes, Buckinghamshire, United Kingdom | Recruiting |
| Croydon University Hospital | Thornton Heath, Croydon, United Kingdom | Recruiting |
| Dorset County Hospital NHS Foundation Trust | Dorchester, Dorset, United Kingdom | Recruiting |
| Poole Hospital | Poole, Dorset, United Kingdom | Recruiting |
| Broomfield Hospital | Chelmsford, Essex, United Kingdom | Recruiting |
| Christie NHS Foundation Trust | Manchester, Greater Manchester, United Kingdom | Recruiting |
| Queen Alexandra Hospital | Portsmouth, Hampshire, United Kingdom | Recruiting |
| University Hospital of South Manchester & Manchester Royal Infirmary | Wythenshawe, Manchester, United Kingdom | Recruiting |
| Musgrove Park Hospital | Taunton, Somerset, United Kingdom | Recruiting |
| Weston General Hospital | Weston-super-Mare, Somerset, United Kingdom | Recruiting |
| Epsom and St Helier's Hospitals NHS Trust | Carshalton, Surrey, United Kingdom | Active Not Recruiting |
| The Royal Marsden NHS Foundation Trust | Sutton, Surrey, United Kingdom | Recruiting |
+ 59 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04050345