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Study identifier: NCT04049331 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Testosterone Replacement in Male Cancer Survivors With Fatigue and Low Testosterone

Condition: Hypogonadism, Male · Fatigue Syndrome, Chronic  ·  Sponsor: Seattle Institute for Biomedical and Clinical Research

PhasePhase 2
Planned participants240
Who can joinMale, 18 Years to 54 Years
Healthy volunteersNo

About this study

The overall goal of this study is to evaluate the effect of a testosterone drug called Depo-Testosterone (or 'testosterone cypionate'), an FDA-approved drug for improving fatigue, sexual function, quality of life, body composition, muscle strength, and physical activity in young cancer survivors who report fatigue and have low testosterone. Main hypothesis is that Testosterone administration in young male cancer survivors who are in remission for at least 1 year, report cancer-related fatigue and have symptomatic testosterone deficiency will be associated with greater improvements in fatigue scores compared with placebo.

This description comes directly from the study's public registry record.

Talk to the study team

Jose M Garcia, MD, PhD  ·  206 764 2984  ·  jg77@uw.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting
Veterans Affairs Puget Sound Health Care SystemSeattle, Washington, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04049331