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Study identifier: NCT04046796 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Genetic Causes of Discrepant Clinic in Monogenic Twins

Condition: Rare Diseases · Genetic Predisposition to Disease  ·  Sponsor: University Hospital Tuebingen

PhaseN/A
Planned participants50
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

In the DISCO-TWIN study (prospective, open-label molecular-genetic study), twin pairs with one healthy and one affected twin with molecularly undiagnosed diseases will be analysed by means of omics technologies and/ or re-analysed using existing datasets. Phenotype and omics data will be shared within the University Hospital Tübingen and with external collaborators to improve the diagnostic rate of the subjects included in the study.

This description comes directly from the study's public registry record.

Talk to the study team

Jeannette Hübener-Schmid, Dr.  ·  +49 7071 29  ·  jeannette.huebener@med.uni-tuebingen.de

Andreas Dufke, PD Dr.  ·  +49 7071 29  ·  andreas.dufke@med.uni-tuebingen.de

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital TübingenTübingen, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT04046796