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Study identifier: NCT04046237 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Impact of Treating Severe Periodontitis on Inflammatory Activity of Atheromatous Plaques in Patients With Acute Myocardial Infarction (AMI)

Condition: Acute Myocardial Infarction · Severe Periodontitis · Carotid Atherosclerosis  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhaseNA
Planned participants210
Who can joinAll sexes, 30 Years to 70 Years
Healthy volunteersNo

About this study

Multicenter randomized clinical trial with two arms in patients hospitalized for an AMI nested in the Frenchie registry. Periodontal therapy is performed by periodontists in the intervention group versus treatment by dental surgeons as part of their usual practice in the control group. For the intervention group, periodontal management will be carried out for a maximum of 6 months after randomisation, prolonged by a follow-up of 6 months including a maintenance visit at M9. All patients will have an FDG-PET at M0 and M12 for evaluation of inflammation on carotid atherosclerotic plaques.

This description comes directly from the study's public registry record.

Talk to the study team

Philippe Gabriel STEG  ·  01 40 25 80 80  ·  gabriel.steg@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Hôpital Bichat, AP-HPParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04046237