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Study identifier: NCT04045691 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment

Condition: Melanoma Stage IV · Melanoma Stage III  ·  Sponsor: Pierre Fabre Pharma GmbH

PhaseN/A
Planned participants750
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

BERING-MELANOMA - designed as a prospective, longitudinal, non-interventional study - investigates real-world effectiveness, quality of life, safety and tolerability of encorafenib plus binimetinib in unresectable advanced or metastatic BRAF(Rapidly Accelerated Fibrosarcoma isoform B)-V600-mutant malignant melanoma after commercial availability of these two products in Germany, Austria and Switzerland. The study focusses on the documentation of the first and second line setting (i.e. after one line of prior checkpoint inhibition) by documenting patients treated according to the SmPC (Summary of Product Characteristics).

This description comes directly from the study's public registry record.

Talk to the study team

Christian A Rosé, MD  ·  +49 761 45261  ·  bering_de@pierre-fabre.com

Andrea Schmidt, MSc  ·  +49 641 94436  ·  ansc@alcedis.de

Always discuss trial participation with your own doctor first.

Locations (59)

11Graz, AustriaRecruiting
13Innsbruck, AustriaRecruiting
14Klagenfurt, AustriaRecruiting
10Linz, AustriaRecruiting
3Linz, AustriaRecruiting
12Salzburg, AustriaRecruiting
22Vienna, AustriaRecruiting
53Vienna, AustriaRecruiting
23Wiener Neustadt, AustriaRecruiting
45Ahaus, GermanyRecruiting
8Aschaffenburg, GermanyRecruiting
56Augsburg, GermanyRecruiting

+ 47 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04045691