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Study identifier: NCT04028401 Synced from ClinicalTrials.gov · July 28, 2026
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Optimization of Skin Preparation to Reduce Cutibacterium Acnes Colonization in Superficial and Deep Samples During Prosthetic Shoulder Surgery in Male Patients

Condition: Cutibacterium Acnes Infection  ·  Sponsor: Nantes University Hospital

PhasePhase 3
Planned participants110
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Infections on joint replacements remain one of the most serious complications of orthopaedic surgery. Despite improvements in skin preparation and antibiotic prophylaxis procedures, the risk of infection of joint prosthesis is still high, particularly for shoulder prostheses, especially in men. One of the bacteria most often involved in post-operative infections for shoulder prosthesis is Cutibacterium acnes (CA). This bacterium is one of the predominant bacteria in pilosebaceous units. Eradication of this micro-organism remains difficult despite the techniques used in the preoperative phase. The objective of this protocol is to evaluate the efficacy of applying a 5% benzoyl peroxide topical during the 5 days preceding the procedure in the surgical skin incision area, which is based on local acne treatment, on the reduction of the CA bacterial load in the dermis of the approach to shoulder arthroplasty in men.

This description comes directly from the study's public registry record.

Talk to the study team

Stéphane CORVEC  ·  0240083955  ·  stephane.corvec@chu-nantes.fr

Always discuss trial participation with your own doctor first.

Locations (6)

CHU d'AngersAngers, FranceRecruiting
CHU de BrestBrest, FranceRecruiting
CHU de LimogesLimoges, FranceRecruiting
CHU de NantesNantes, FranceRecruiting
CHU de RennesRennes, FranceRecruiting
CHU de ToursTours, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04028401