Condition: Eosinophilia · Hypereosinophilic Syndrome · Sponsor: University Hospital, Lille
Unexplained chronic hypereosinophilia (HE) and hypereosinophilic syndromes (HES) are heterogeneous regarding the organ involvements (heart, lungs, skin, .. or none), the evolutionary profiles, the response to treatments. Underlying mechanisms are largely unknown and may associate genetic predisposing factors (germinal ? somatic?), environmental factors (alimentation, tobacco use, hormones, infections, ..) The COHESion study aims to study all clinical and biological characteristics of HE/HES patients and their evolutionary profiles, with a focus on genetic factors and the mechanisms supporting transitory or persistant chronic HE/HES (in absence of any well identified extrinsic trigger like drugs, parasitosis, ..)
This description comes directly from the study's public registry record.
Guillaume Lefevre, MD · 03 20 44 55 72 · Guillaume.lefevre@chru-lille.fr
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| Hôpital Roger Salengro, CHU | Lille, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04018118