Condition: B-cell Leukemia · Sponsor: Shenzhen Geno-Immune Medical Institute
This study will evaluate safety and efficacy of a combination of 4th generation chimeric antigen receptor gene-modified T cells targeting CD19 negative ALL that express CD22, CD123, CD38, CD10, CD20 and TSLPR, as many patients developed CD19-negative disease after CD19 CART immunotherapy. Clinical response and development of a standardized lentiviral vector and cell production protocol will be investigated. This is a phase I/II trial enrolling patients from multiple clinical centers.
This description comes directly from the study's public registry record.
Lung-Ji Chang, PhD · +86 0755-86573763 · c@szgimi.org
Always discuss trial participation with your own doctor first.
| Shenzhen Geno-immune Medical Institute | Shenzhen, Guangdong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04016129