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Study identifier: NCT04008563 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Bariatric Surgery for Fertility-Sparing Treatment of Atypical Hyperplasia and Grade 1 Cancer of the Endometrium

Condition: Endometrial Cancer · Atypical Hyperplasia · Bariatric Surgery Candidate  ·  Sponsor: University Health Network, Toronto

PhaseNA
Planned participants36
Who can joinFemale, 18 Years to 41 Years
Healthy volunteersNo

About this study

A growing population of young women with obesity are developing atypical hyperplasia (pre-cancer) and endometrial cancer. Progestin is the standard treatment for women who wish to preserve fertility, but this approach does not address the underlying cause of endometrial cancer/atypical hyperplasia (obesity); thus response rates are low and recurrence rates are high. Significant weight loss by bariatric surgery, in combination with progestin therapy may result in greater and more durable response rates.

This description comes directly from the study's public registry record.

Talk to the study team

Tara Zad  ·  416-946-4501  ·  Tara.Zad@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Princess Margaret HospitalToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT04008563