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Study identifier: NCT04005976 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

Condition: Aortic Aneurysm · Aortic Dissection · Aortic Diseases  ·  Sponsor: The University of Texas Health Science Center, Houston

PhaseN/A
Planned participants5000
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersYes

About this study

The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenotype associated with these genes, and determine genetic and environmental modifiers of H-TAD.

This description comes directly from the study's public registry record.

Talk to the study team

Dianna M Milewicz, MD, PhD  ·  713-500-6725  ·  Dianna.M.Milewicz@uth.tmc.edu

Ernesto Calderon Martinez, MD  ·  (713) 500-6715  ·  Ernesto.CalderonMartinez@uth.tmc.edu

Always discuss trial participation with your own doctor first.

Locations (20)

HOAG memorial hospital presbyterianNewport Beach, California, United StatesRecruiting
Hoag Memorial Hospital PresbyterianNewport Beach, California, United StatesRecruiting
Sutter HealthSacramento, California, United StatesRecruiting
University of KentuckyLexington, Kentucky, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
University of MichiganAnn Arbor, Michigan, United StatesRecruiting
Washington University in St. LouisSt Louis, Missouri, United StatesRecruiting
University of Nebraska Medical CenterOmaha, Nebraska, United StatesRecruiting
St. Francis Hospital (Catholic Health)Roslyn, New York, United StatesRecruiting
Oregon Health & Science UniversityPortland, Oregon, United StatesRecruiting
Baylor College of MedicineHouston, Texas, United StatesRecruiting
Texas Children's HospitalHouston, Texas, United StatesRecruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04005976