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Study identifier: NCT03997968 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors

Condition: Malignancy · Non-hodgkin Lymphoma · Multiple Myeloma  ·  Sponsor: Cyteir Therapeutics, Inc.

PhasePhase 1/Phase 2
Planned participants169
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial is an interventional, active-treatment, open-label, multi-center, Phase 1/2 study. The study objectives are to assess the safety, tolerability and pharmacokinetics (PK) of CYT-0851 in patients with relapsed/refractory B-cell malignancies and advanced solid tumors and to identify a recommended Phase 2 dose as a monotherapy and in combination with chemotherapy for evaluation in these patients.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (16)

University of California San FranciscoSan Francisco, California, United States
Stanford Comprehensive Cancer CenterStanford, California, United States
Sarah Cannon Research Institute at HealthONEDenver, Colorado, United States
Florida Cancer Specialists and Research InstituteSarasota, Florida, United States
Massachusetts General HospitalBoston, Massachusetts, United States
Dana Farber Cancer InstituteBoston, Massachusetts, United States
University of MichiganAnn Arbor, Michigan, United States
Mayo ClinicRochester, Minnesota, United States
John Theurer Cancer Center at HUMCHackensack, New Jersey, United States
NYU Langone HealthNew York, New York, United States
Oklahoma University-Stephenson Cancer CenterOklahoma City, Oklahoma, United States
Thomas Jefferson University, Sidney Kimmel Cancer CenterPhiladelphia, Pennsylvania, United States

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03997968