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Study identifier: NCT03984643 Synced from ClinicalTrials.gov · July 28, 2026
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Algorithms for Programming DBS Systems for ET

Condition: Essential Tremor  ·  Sponsor: University of Minnesota

PhaseNA
Planned participants25
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersNo

About this study

Deep brain stimulation (DBS) targeting the Vim thalamus (ventralis intermedius nucleus) is an FDA-approved neuromodulation therapy for treating postural and action tremor in individuals with essential tremor (ET). The success of this treatment, however, is highly dependent on the ability of clinicians to identify therapeutic stimulation settings through a laborious programming process. There is a strong and growing clinical need for new approaches to provide clinicians with more efficient guidance on how to titrate stimulation settings. This study will leverage subject-specific computational models that can predict neural activation of axonal pathways adjacent to the active electrode(s) and implicated in the therapeutic mechanisms of Vim-DBS to in turn guide clinicians with which stimulation settings are likely to be the most therapeutic on tremor.

This description comes directly from the study's public registry record.

Talk to the study team

Matthew Johnson, PhD  ·  6126266492  ·  john5101@umn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of MinnesotaMinneapolis, Minnesota, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03984643