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Study identifier: NCT03958565 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations.

Condition: Carcinoma, Non-Small-Cell Lung  ·  Sponsor: University of Colorado, Denver

PhaseN/A
Planned participants100
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess percentage reduction in the of urine NTX and serum CTX , in patients with NSCLC and bone metastases 1) with actionable driver oncogene on standard of care (SOC) TKI at 3 months post treatment and 2) without actionable mutations on standard of care therapy (chemotherapy/immunotherapy) treated with zoledronic acid or denosumab at the same time period.

This description comes directly from the study's public registry record.

Talk to the study team

Febin Elias  ·  13037249459  ·  febin.elias@cuanschutz.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of Colorado HospitalAurora, Colorado, United StatesRecruiting
Lone Tree Medical CenterLone Tree, Colorado, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03958565