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Study identifier: NCT03955445 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

Condition: C3 Glomerulopathy · Immune-complex-membranoproliferative Glomerulonephritis  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 3
Planned participants225
Who can joinAll sexes, 12 Years to 100 Years
Healthy volunteersNo

About this study

This is an open-label extension study to evaluate the long-term efficacy, safety and tolerability of iptacopan in subjects with C3 glomerulopathy or idiopathic immune-complex-membranoproliferative glomerulonephritis

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111

Always discuss trial participation with your own doctor first.

Locations (53)

Childrens Hospital ColoradoAurora, Colorado, United StatesRecruiting
Georgia Nephrology Research InstLawrenceville, Georgia, United StatesRecruiting
University of Iowa Health CareIowa City, Iowa, United StatesRecruiting
University of MinnesotaMinneapolis, Minnesota, United StatesRecruiting
Col Uni Med Center New York PresbyNew York, New York, United StatesRecruiting
Novartis Investigative SiteCABA, Buenos Aires, ArgentinaRecruiting
Novartis Investigative SiteBuenos Aires, ArgentinaRecruiting
Novartis Investigative SiteBelo Horizonte, Minas Gerais, BrazilRecruiting
Novartis Investigative SiteRecife, Pernambuco, BrazilRecruiting
Novartis Investigative SitePorto Alegre, Rio Grande do Sul, BrazilRecruiting
Novartis Investigative SiteBotucatu, São Paulo, BrazilRecruiting
Novartis Investigative SiteSão Paulo, São Paulo, BrazilRecruiting

+ 41 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03955445